منابع مشابه
In vitro spermatogenesis
The generation of functional sperm in vitro has been a goal for almost a century. Until recently, researchers have only succeeded in reproducing the early steps of spermatogenesis. This is not surprising given that spermatogenesis is a complicated process that requires the coordinated efforts of germ cells and several somatic cells within the tubular structure of the testis. Finally-last year-S...
متن کاملModels of in vitro spermatogenesis
Understanding the mechanisms that lead to the differentiation of male germ cells from their spermatogonial stem cells through meiosis to give rise to mature haploid spermatozoa has been a major quest for many decades. Unlike most other cell types this differentiation process is more or less completely dependent upon the cells being located within the strongly structured niche provided by mature...
متن کاملIn Vitro Spermatogenesis in Explanted Adult Mouse Testis Tissues
Research on in vitro spermatogenesis is important for elucidating the spermatogenic mechanism. We previously developed an organ culture method which can support spermatogenesis from spermatogonial stem cells up to sperm formation using immature mouse testis tissues. In this study, we examined whether it is also applicable to mature testis tissues of adult mice. We used two lines of transgenic m...
متن کاملThe dynamics of Drosophila melanogaster spermatogenesis in in vitro cultures.
A photographic description of meiosis and spermatogenesis in single sperm cysts of Drosophila melanogaster cultured in vitro is presented. In addition to the utility of this description for the study of spermatogenesis in whole live testes, the culture procedure provides a means for studying the dynamic development of individual sperm cysts from flies carrying male-sterile mutations, as illustr...
متن کاملCryopreservation of testis tissues and in vitro spermatogenesis
Cancer treatments, either chemo- or radiotherapy, may cause severe damage to gonads which could lead to the infertility of patients. In post-pubertal male patients, semen cryopreservation is recommended to preserve the potential to have their own biological children in the future; however, it is not applicable to prepubertals. The preservation of testis tissue which contains spermatogonial stem...
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ژورنال
عنوان ژورنال: Spermatogenesis
سال: 2012
ISSN: 2156-5562
DOI: 10.4161/spmg.22069